Systemic effects of pesticides are those that occur:

Systemic effects of pesticides are indeed those that occur throughout the body. This term refers to the way a pesticide is absorbed and then distributed via the bloodstream to various tissues and organs, rather than being limited to the site of application. When a pesticide is systemic, it means that once absorbed, it affects not just the area where it was applied but can influence numerous biological systems within the organism.

For instance, some systemic pesticides can be taken up by plants and then affect insect pests that consume any part of the plant. In humans or other animals, systemic effects can lead to a range of potential health impacts depending on how the pesticide interacts with body systems and metabolism.

In contrast, the other options focus on specific localized effects or parts of the body. The point of contact refers to immediate effects where the pesticide is first applied, such as irritation or harm. The suggestion that effects occur only in the skin or solely within the digestive system implies a more restricted scope of influence, which does not accurately reflect the nature of systemic pesticide action. Understanding systemic effects is crucial for recognizing the potential broad impact of pesticide exposure, especially in terms of safety and regulatory considerations.